Systems biology moves beyond studying individual genes or proteins to understand how they work together as a complex, living network. Instead of looking at isolated parts, this field examines the intricate conversations between molecules that drive life, revealing how cellular systems respond to changes and maintain balance. It is a holistic approach that turns vast amounts of data into a coherent story of how organisms function as a whole.
At Gist.Science, we ensure these breakthroughs remain accessible to everyone by processing every new preprint in this category directly from bioRxiv. Our team generates both plain-language explanations for the curious mind and detailed technical summaries for researchers, bridging the gap between rapid scientific discovery and clear understanding.
Below are the latest preprints in systems biology, freshly curated and summarized to help you navigate the cutting edge of network science.
📄 systems biology
COUPLING OF ENVIRONMENTAL AND DIRECT TRANSMISSIONMECHANISMS: ANALYSIS OF A SIMPLE MODEL
This paper analyzes a simple epidemiological model coupling environmental and direct transmission mechanisms, revealing that their interaction induces complex dynamics such as multistability, backward bifurcations, and sensitivity to initial conditions governed by distinct environmental and combined threshold quantities.
Islas, J. M., Espinoza, B., Velasco-Hernandez, J. X.2026-01-23
📄 systems biology
Mitochondrial ribosome content as a proxy for respiration
This study demonstrates that mitochondrial ribosome content serves as a robust linear proxy for cellular respiration in exponentially growing yeast, offering a novel method to infer metabolic activity and identify overflow conditions.
Mairet, F.2026-01-22
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